Based on the hit podcast of the same name, Burden of Guilt follows Tracyraquel Berns' emotional journey to unravel the convoluted excuses that were given about her baby brother Matthew's sudden death when she was just two years old. Though initially ruled an accident, the mystery of how Matthew died haunts Tracyraquel throughout her childhood. After years of lies and unanswered questions, she obtains Matthew's medical records and uncovers a shocking detail; she learned she was blamed for his death. Tracyraquel embarks on a relentless search to expose the darkest and deepest secret of her troubled family. Her investigation leads the authorities in Dekalb County Georgia to an unprecedented decision to exhume Matthew's body 25 years after his death, which reveals that his death was a homicide.